The name ''Orticaia'' appears to be derived from the fact that the church was originally located in an area that was either invaded by nettle (''ortica'') or rich in kitchen gardens ('orti'').
The Romanesque church dates from the 12th century but has been altered on several occasions. The low bell tower was built in the 17th century directly on the apse wall. The façade is built of stone and bricks in its lower and upper portions respectively, and is pierced asymmetrically by a square window to the left of the entrance door. The aisleless interior is decorated with baroque frescoes attributed to the Melani brothers. Notable among these is the ''Conversion of St. Ranieri'', believed to have occurred in this church.